Valerian 10% & GABA, TPA alkaloid extract
Valerian (Valeriana officinalis) is a perennial plant from the honeysuckle family, native to Europe and parts of Asia. Its root has been used in Western herbal tradition for centuries and is recognised in the European Union as a traditional herbal medicine for mild nervous tension and sleep problems. The scientific evidence for this effect is mixed: some studies report a shorter time to fall asleep and better sleep quality, while others find no clear effect; the effect seems most consistent for mild, temporary complaints and only after continuous use of two to four weeks.
This extract adds GABA (gamma-aminobutyric acid), naturally the brain's main inhibitory neurotransmitter. Whether orally taken GABA crosses the blood-brain barrier sufficiently is still debated in the scientific literature, so treat it as a supporting ingredient alongside the valerian rather than the main active substance.
The extract is made using the TPA method (Total Purified Alkaloids): the valerian alkaloids are isolated through several extraction and purification steps to a concentration of 10% and then, together with GABA, dissolved in an ethanol and water base. The result is a clear liquid extract without plant residue, wax or chlorophyll, more concentrated than an ordinary valerian tincture.
Dosage
Start with 5 to 10 drops (about 0.25-0.5 ml) half an hour to two hours before bedtime and assess your reaction before increasing the dose. Valerian does not work acutely against acute stress; a noticeable effect for mild complaints usually requires continuous use of two to four weeks.
Use
The extract can be taken sublingually (drops under the tongue) or diluted in a small amount of water; the taste is sharp due to the ethanol content, so diluting makes it more pleasant to take. Valerian can make you drowsy for the following hours: don't drive or operate machinery shortly after taking it. Do not combine it with alcohol or sedative medication such as benzodiazepines without consulting your doctor, and do not use it during pregnancy or breastfeeding. See a doctor if symptoms persist or worsen after two weeks.
Storage
Store the extract cool, dark and upright with the cap closed, out of reach of children. Close the cap tightly after use to prevent the ethanol from evaporating. At Dutch-Smart you will also find the alkaloid extracts of Happy Skullcap and Passionflower in the same range, two other mild calming herbs.
