Salvia divinorum 80X extract
The 80X designation indicates the concentration ratio relative to untreated dried leaves. The extract contains 288 mg of salvinorin A per gram and is produced by impregnating dried Salvia divinorum leaves with a concentrated salvinorin A solution. After drying, this yields a homogeneous product with a consistent active ingredient content. The package size is 0.5 grams; at the recommended starting dose of 0.01 grams, this allows for approximately 50 sessions.
The 80X is the highest concentration in the Salvia divinorum range at Dutch-Smart. Moving up to the 80X is only advisable if the 40X variant has been used extensively and without unexpected effects.
Active ingredient and effects
The psychoactive effect of Salvia divinorum is entirely due to salvinorin A, a terpenoid compound that is unique among psychoactive plant substances. It is the only known potent non-alkaloid psychedelic and acts as a selective kappa-opioid receptor agonist, with no affinity for the serotonin 5-HT2A receptor targeted by classic psychedelics such as psilocybin and LSD.
Users report a complete transformation of perception at high concentrations of salvinorin A: a sense of merging with the environment, a strongly distorted sense of time, and an experience in which familiar reality temporarily disappears entirely. When smoked, the peak phase lasts two to five minutes; the total duration of effect is typically five to ten minutes. With 288 mg per gram, the 80X delivers more than twice as much active ingredient at a dose of 0.01 grams compared to the same dose of the 40X.
Origin and cultural context
Salvia divinorum originates from the Oaxaca mountains in southern Mexico, where the plant was cultivated for centuries in small, isolated communities by the Mazatec. In shamanic rituals, the leaves were traditionally chewed or taken as an infusion, resulting in a slower onset and a duration of one to two hours, which differs significantly from the minutes typically experienced when smoking the extract. Both methods of use activate the same active compound, but the pharmacological pathway and the experiential profile differ significantly.
The 80X extract is far removed from the traditional method of use. The concentration and the inhalation method produce effects that are not comparable in speed and intensity to the ritual context of origin.
Use and Dosage
Salvia extract is smoked using a pipe or bong. The starting dose for the 80X is 0.01 grams per session. This is also the minimum amount that can be accurately weighed using a precision scale that measures hundredths of a gram. The amount is completely inhaled in one long drag and held in the lungs for as long as possible, usually 20 to 30 seconds. The onset occurs within 5 to 30 seconds after exhaling.
With the 80X, never estimate by eye and never use a standard kitchen scale. Start with the lowest possible amount and wait at least one day before considering a follow-up dose. A hookah or bong cools the smoke; vaporization requires approximately 240 °C using a portable vaporizer.
Storage
Store the extract in a dry, cool place away from direct sunlight. Salvinorin A is sensitive to light degradation and oxidation; store in the original sealed packaging. When stored correctly, potency remains stable for a long time.
Harm reduction
Salvia divinorum is one of the most potent known psychoactive plants. At the 80X concentration, complete disorientation is virtually certain. The ability to exercise self-control, spatial awareness, and recognition of the surroundings may be completely lost during the peak phase.
Never use alone. A sober companion who remains present for the entire duration and can physically intervene is not a recommendation but a requirement at the 80X concentration. Choose a safe sitting position on the floor or in a low chair; never stand or be near water, fire, or stairs. Remove all loose and dangerous objects from the immediate vicinity before beginning.
Do not combine salvia with alcohol, cannabis, benzodiazepines, or other psychoactive substances. Driving and operating machinery are strictly discouraged during and for at least several hours after use. Do not use if you have a history of psychiatric conditions, particularly a predisposition to psychosis or dissociative disorders, and do not use during pregnancy or while breastfeeding.
Salvia divinorum is not listed under the Opium Act in the Netherlands and is legally available to individuals 18 years of age and older. Check the laws in your own country before purchasing or importing.
Comprehensive safety information on psychoactive herbs can be found in the Dutch-Smart knowledge base.
Frequently Asked Questions
What makes the 80X different from the 40X?
The 80X contains 288 mg of salvinorin A per gram, exactly double that of the 40X. At the same dose, the 80X therefore delivers twice as much active ingredient. The intensity of the effects is correspondingly higher, and the threshold for an overwhelming experience is significantly lower. Use the 80X only if you are very familiar with the 40X and know how you react to it.
How many grams should I use per session?
The starting dose is 0.01 grams, weighed with a precision scale that measures hundredths of a gram. This is the absolute minimum; never estimate by eye. Never take a second dose while the first is still active, and wait at least one day before taking a follow-up dose.
How long do the effects last with the 80X?
When smoked, the effects begin within seconds. The peak phase lasts two to five minutes, and the total duration of the effects is typically five to ten minutes. A mild after-effect phase may persist for another 15 to 30 minutes. The short duration is in no way proportional to the intensity: with the 80X, the experience during the peak phase is completely overwhelming for most users.
Is this extract legal in the Netherlands?
Yes. Salvia divinorum and its extracts are not covered by the Opium Act and are legally available for purchase in the Netherlands by individuals 18 years of age and older. In a number of other European countries, the plant is prohibited; check local regulations before purchasing or importing.